γ-Carboxylation

Overview γ-Carboxylation occurs mainly in proteins related to blood coagulation. Glutamic acid residues are carboxylated by the enzyme glutamyl carboxylase in γ-position in the presence of oxygen and carbon dioxide. Vitamin K is required as a cofactor. pKa NC Loss Gain Deltamass H AA UV-Spec Pattern Acidic 2.03 Yes H CHO2 Av: 44.0095M: 43.9898 – […]